Table 1.

Circulating levels of IGF-1, insulin, and leptin in cixutumumab-treated chow-fat fed mice in fed state (A12 denotes cixutumumab, IC denotes isotype control, data expressed as mean (SEM)* denotes P < 0.05).

Diet	Chow Mean (SEM)
	Control	A12
IGF-1 (pg/mL)	654.19 (32.09), n = 5	1165.43 (81.68), n = 5 p = 0.001
Insulin (ng/mL)	3.368 (0.313), n = 6	7.262 (0.804), n = 6 p = 0.001
Leptin (ng/mL)	0.108 (0.017), n = 5	0.150 (0.01), n = 5 p = ns