. 2022 Jun 19;17(7):1937–1950. doi: 10.1021/acschembio.2c00378

Table 3. Structure–Activity Relationship of the N-(1H-indol-6-yl)acetamide Series of 3-Cyanopyrazolo[1,5-a]pyrimidines 16–33^a^,^b.

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In-cell target engagement of CSNK2A2-nLuc in HEK293 cells.

Inhibition of MHV-nLuc replication in DBT cells. All values are the mean of three assays with range ± 15%. i.a. inactive.

Table 3. Structure–Activity Relationship of the N-(1H-indol-6-yl)acetamide Series of 3-Cyanopyrazolo[1,5-a]pyrimidines 16–33a,b.