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. 2022 Jun 13;13:889404. doi: 10.3389/fphar.2022.889404

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Copyright © 2022 Gao, Liu, Yao, Zhang, Yang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PNS treatment improved the recovery of neurological functions in ME rats. Comparison of neurological score, forepaw outreaching score and weight percentage were measured at day 1, 3, 7, and 14 after ME surgery at different time nodes. Rope climbing test score were detected at day 14 after ME surgery. (A) Neurological score (B) Forepaw outreaching test score (C) Rope climbing test score (D) Weight percentage. The data in experiment (A,B,D) were shown as means and the data in experiment (C) were presented as means ± standard deviation (n = 9 animals per group). *p < 0.05, **p < 0.01 versus Sham group; ^# p < 0.05, ^## p < 0.01 versus ME group.