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. 2022 Aug 29;6(17):4975–4982. doi: 10.1182/bloodadvances.2022007940

Table 3.

Decision thresholds per critical outcome

Outcome Utility value,mean (SD) Decision thresholds (events per 1000; 95% CI)
Trivial/small Small/moderate Moderate/large
Mortality 0 16 (9 to 22) 31 (22 to 39) 60 (46 to 73)
PE, moderate 0.42 (0.15) 27 (15 to 38) 53 (38 to 68) 103 (80 to 125)
Proximal DVT, moderate 0.58 (0.14) 37 (21 to 53) 73 (53 to 94) 142 (110 to 173)
Major bleeding 0.33 (0.23) 23 (13 to 33) 46 (33 to 59) 89 (69 to 109)
Ischemic stroke, severe 0.14 (0.10) 18 (10 to 26) 36 (26 to 46) 69 (54 to 85)
Intracranial hemorrhage 0.12 (0.10) 18 (10 to 25) 35 (25 to 45) 68 (53 to 83)
Multiple organ failure 0.15 (0.14) 18 (10 to 26) 36 (26 to 46) 70 (54 to 86)
ST-elevation MI (STEMI) 0.31 (0.19) 23 (13 to 32) 44 (32 to 57) 86 (67 to 105)
Limb amputation 0.26 (0.16) 21 (12 to 30) 41 (30 to 53) 80 (63 to 98)
Long-term invasive ventilation 0.20 (0.12) 20 (11 to 28) 38 (28 to 49) 74 (58 to 91)