Table 3. Differences between approaches.
| Factors | Supraorbital | Transnasal | p -Value |
|---|---|---|---|
| n | 20 | 11 | – |
| Mean age (y) | 60.7 | 56.0 | 0.382 |
| BMI (kg/m 2 ) | 30.5 | 34.2 | 0.299 |
| Female gender (%) | 15 (75%) | 7 (64%) | 0.505 |
| Pre-op tumor volume (cm 3 ) | 8.0 | 7.4 | 0.871 |
| Pre-op visual acuity deficit | 12 (63%) | 7 (64%) | 0.713 |
| Pre-op anopsia | 13 (68%) | 7 (64%) | 0.930 |
| Pre-op anosmia | 4 /16(25%) | 1/3 (33%) | N/A |
| Pre-op FLAIR change | 7 (35%) | 2 (18%) | 0.429 |
| No lateral or superior extension from CN II | 9 | 6 | – |
| Lateral extension from CN II | 2 | 2 | – |
| Superior extension from CN II | 5 | 3 | – |
| Lateral and superior extension from CN II | 4 | 0 | – |
| Anticonvulsant use | 12 (60%) | 2 (18%) | 0.057 |
| Lumbar drain use | 0 (0%) | 8 (73%) | <0.0001 |
| Post-op tumor volume (cm 3 ) | 0.2017 | 3.2 | 0.0439 |
| Extent of resection (%) | 88.1% | 57.9% | 0.016 |
| Post-op visual acuity deficit | 2 (10%) | 6 (54%) | 0.004 |
| Post-op anopsia | 4 (20%) | 6 (54%) | 0.011 |
| Post-op anosmia | 4/14 (29%) | 1/3 (33%) | N/A |
| Post-op seizure | 3 (15%) | 0 (0%) | 0.177 |
| Post-op radiographic stroke | 3 (15%) | 0 (0%) | 0.535 |
| CSF leak | 0 (0%) | 2 (18%) | 0.118 |
| Post-op FLAIR change | 7 (35%) | 4 (36%) | 1.000 |
| Post-op DWI signal | 7 (35%) | 0 (0%) | 0.033 |
| Length of stay (d) | 3.4 | 6.1 | <0.001 |
| Subsequent surgery for recurrence | 4 (20%) | 2 (18%) | 1.000 |
| Post-op radiation | 6 (30%) | 2 (18%) | 0.676 |
Abbreviations: BMI, body mass index; CN, cranial nerve; CSF, cerebrospinal fluid; DWI, diffusion-weighted imaging; FLAIR, fluid-attenuated inversion recovery; N/A, not available; Post-op, postoperative; Pre-op, preoperative.