Table 2.

Comparison between π signature and the other previously established pyroptosis-related signatures.

Cancer subtype	Signatures	Cancer types	AUC at 1 year	AUC at 3 years	AUC at 5 years	References
PPRC	π signature	BRCA, MESO, and SKCM	0.787	0.774	0.748
	Other signatures	Breast cancer (BRCA)	0.756	0.752	0.723	[27]
		Skin cutaneous melanoma (SKCM)	—	0.64	0.711	[28]
PNRC	π signature	GBM, KIRC, LGG, PAAD, and UVM	0.844	0.861	0.829
	Other signatures	Glioma (GBM and LGG)	0.669	0.713	0.709	[29]
		Kidney renal clear cell carcinoma (KIRC)	0.57	0.62	0.65	[30]
		Pancreatic adenocarcinoma (PAAD)	0.596	0.687	0.732	[31]
		Uveal melanoma (UVM)	0.79	0.854	0.886	[32]