Table 1.

Drug related databases and their information of the data type, data statistics, availability, and programmatic access are summarized.

	Database name	Type	Statistic	Availability	Programmatic access
1	PubChem	Structural and common data	PubChem contains 237 million bioactivities for three million compounds, determined in over 1.2 million biological assay experiments	Open source	Rest API
2	ChEMBL	Structural and common data	more than 2.2 million distinct compound structures, with 5.4 million activity values from more than 1.5 million assays.	Open source	Rest API
3	STITCH	DTIs	0.5 million Chemicals, 9.6 million proteins, and 1.6 billion interactions	Open source	Rest API
4	TTD	DTIs	33598 drug-like agents, 1102 targets and their interactions.	Open source	Django Rest API
5	DrugBank	Common resource	Total small molecules 11937, Biotech drugs 2687, approved drugs 4243, approved small molecules 2725	Open source and commercial	–
6	BindingDB	DTIs	containing ∼20 000 experimentally determined binding affinities of protein–ligand complexes, for 110 protein targets including isoforms and mutational variants, and ∼11 000 small molecule ligands	Open source and commercial	Rest API
7	DT-Web	DTIs	–	Open source	R-CMD
8	TCGA	Perturbation Data	TCGA generated over 2.5 petabytes of genomic, epigenomic, transcriptomic, and proteomic data	Open source	–
9	SIDER	Side effect data	Side effects of 1400 FDA approved Drugs	Open source	–
10	PharmaGKB	Drug-Disease associations	–	–	API
11	GEO	Perturbation Data	Contains around 4348 datasets, 23,172 platforms, and 5,029,933 samples.	Open source	–
12	LINCS	Perturbation Data	Gene expressions of thousands of perturbations	Open source	–