Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 21;22(8):701–712. doi: 10.1007/s12012-022-09746-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — Impact of DYRK1A overexpression on the relative abundance of TNNT2 transcript variants in iPSC cardiomyocytes transfected with SRSF6. A Relative abundance of TNNT2 transcript variants in cells transfected with an SRSF6-HA (SRSF6) or co-transfected with DYRK1A-GFP and SRSF6 expression constructs (SRSF6-DYRK1A). B Relative DYRK1A mRNA fold expression in transfected cells. C Relative abundance of cTnT1 and cTnT2 (left), cTnT3 (center), and cTnT4 (right) transcript variants. Horizontal bars show the mean ± SD from three independent transfections per condition, with 2–3 determinations performed in triplicate. ***P < 0.001, *P < 0.05, ns not significant, Student’s t test. D Impact of SRSF6 overexpression on the relative abundance of cTnT1 and cTnT2 in cells with basal levels of DYRK1A (left), or overexpressing DYRK1A (right). **P < 0.01, *P < 0.05, ns not significant. One-way ANOVA (Tukey’s test)