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. Author manuscript; available in PMC: 2023 Jan 25.
Published in final edited form as: ACS Nano. 2021 Dec 28;16(1):683–693. doi: 10.1021/acsnano.1c08178

Scheme 1. Synthetic Pathway and Charge-Dependent Behaviors of Functionalized PNC.

Scheme 1.

(a) Schematic of simple synthesis of dye-loaded PNCs. PNC was synthesized using a supramolecular template (PBDT-TA). By virtue of glue-like nature of PDA, PNC was loaded with small molecular dyes (e.g., NB, AA, and MB) via multiple interactions. (b) During heparin interactions, negatively charged PNCs released the loaded dyes in PNCs, while positively charged PNCs showed particle aggregation that increased PA signal.