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. 2022 Jun 14;13:913178. doi: 10.3389/fimmu.2022.913178

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Copyright © 2022 Wang, Li, Liu, Luo, Guo, Yang, Xu, Ma and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of M1-type macrophages and M2-type macrophages, in terms of stimulatory factors, transcription factors, released mediators, and functional properties during the process of PALI. AP-1, activating protein-1; ARG1, arginase 1; CMyC, transcription factor CMyC; GM-CSF, granulocyte-macrophage colony-stimulating factor; IFN-γ, interferon γ; IRF, interferon regulatory factor; KLF-4, krüppel-like factor 4; LPS, lipopolysaccharide; NF-κB, nuclear transcription factor κB; ROS, reactive oxygen species; STAT, signal transduction and activation of transcription factor; TGF-β, transforming growth factor ß; VEGF, vascular endothelial growth factor.