Table 3.
Correlation analysis between regional brain atrophy and WMHr.
| NC | AD | |||
|---|---|---|---|---|
| rS | p value | rS | p value | |
| QMTA | 0.288 | <0.001* | 0.281 | 0.011 |
| Frontal Lobe Atrophy | −0.029 | 0.712 | −0.115 | 0.312 |
| Occipital Lobe Atrophy | 0.042 | 0.598 | 0.037 | 0.747 |
| Temporal Lobe Atrophy | 0.225 | 0.004* | 0.285 | 0.011 |
| Parietal Lobe Atrophy | −0.147 | 0.063 | −0.204 | 0.070 |
| Cingulate Lobe Atrophy | 0.199 | 0.012 | 0.072 | 0.523 |
| Insular Atrophy | 0.392 | <0.001* | 0.406 | <0.001* |
NC, normal cognitively; AD, Alzheimer's disease; WMHr, quantitative WMH ratio; QMTA, quantitative medial temporal atrophy; rs, Spearman r. The p-value was obtained by Spearman correlation coefficient values. *means statistical significance after Bonferroni correction.