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. 2022 Jun 14;12:873096. doi: 10.3389/fcimb.2022.873096

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Copyright © 2022 Tang, Yi, Lu, Chen and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BHD modulated the overall structure and composition of the gut microbiota in rats with CI. (A) Species accumulation curve. (B) Shannon diversity index. (C) PCoA based on unweighted UniFrac distances. (D) Ternary phase diagram. (E) Community structure bar plot at the genus level. **p < 0.01, *p < 0.05. ns, not statistically significant. Con, control group; Mod, model group; BHD, BHD group. n = 8 per group.