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Effects of BHD on microglia in the brain and peripheral proinflammatory cytokines in rats with CI. (A, B) Quantification of Iba-1-positive cells in the ischemic brain tissue of rats (n = 4 per group). (C-E) Serum levels of IL-1β, IL-6, and TNF-α (n = 6 per group). All the data are presented as the mean ± SD. Differences were assessed by one-way ANOVA: ***p < 0.001, **p < 0.01, *p < 0.05. ns, not statistically significant. n = 8 per group.
