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Stability results of voxtalisib in rat plasma under different conditions (n = 5).
| Analyte | Concentration (ng/ml) | Room temperature, 3 h | Auto-sampler 10°C, 4 h | Three freeze-thaw | −80°C, 3 weeks | ||||
|---|---|---|---|---|---|---|---|---|---|
| RSD (%) | RE (%) | RSD (%) | RE (%) | RSD (%) | RE (%) | RSD (%) | RE (%) | ||
| Voxtalisib | 2 | 8.5 | 2.0 | 4.4 | −1.8 | 8.2 | 2.2 | 8.2 | 7.4 |
| 800 | 5.5 | 14.6 | 4.5 | 7.0 | 2.4 | 10.6 | 3.8 | 0.9 | |
| 1600 | 5.1 | 7.1 | 5.1 | 4.6 | 3.8 | 9.5 | 6.5 | −10.8 | |
