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. 2022 Jun 2;13:918479. doi: 10.3389/fphar.2022.918479

TABLE 2.

List of interacting residues of MAP kinase p38 alpha and DHFR to CIN.

S. No. Target Interacting Residues
Close contacts Other soft interactions
1. MAP kinase p38 alpha Tyr35, Val38, Lys53, Met109, and Phe169 Val30, Val38, Ala51, Thr106, His107, Leu108, Gly170, and Leu171
2. Dihydro Folate Reductase Ala9, Phe34, Ile60, and Tyr121 Ile7, Ile16, Leu22, Trp24, Phe31, Thr56, Leu67, and Val115