Table 1.
Unilateral TLE patient information by group and 1-year seizure outcome
| Group | Model | Test | Left-out | ||||
|---|---|---|---|---|---|---|---|
| 1-year outcome | Engel Ia | mixed | Engel Ia | Engel Ib-d | Engel II | Engel III–IV | P |
| # Patients | 9 | 5 | 15 | 11 | 5 | 7 | |
| Age (years: mean ± std) | 42.3 ± 13.1 | 34.2 ± 18.8 | 45.4 ± 13.0 | 34.1 ± 9.8 | 38.0 ± 5.4 | 39.2 ± 5.0 | 0.101 |
| Sex (#F, %) | 7, 77.7% | 3, 60% | 4, 26.6% | 7, 63.6% | 3, 60% | 2, 28.5% | 0.192 |
| Handedness (# Right, %) | 8, 88.8% | 3, 60% | 11, 73.3% | 11, 100% | 4, 80% | 6, 85.7% | 0.352 |
| Side (# Right, %) | 6, 66.6% | 3, 60% | 10, 66.6% | 9, 81.8% | 5, 100% | 3, 42.8% | 0.122 |
| Age of onset (years: mean ± std) | 16.0 ± 14.9 | 16.5 ± 26.7 | 24.3 ± 16.8 | 13.4 ± 9.1 | 23.2 ± 12.3 | 22.7 ± 12.6 | 0.211 |
| Duration (years: mean ± std) | 26.3 ± 14.2 | 17.8 ± 15.4 | 21.0 ± 17.2 | 20.7 ± 13.6 | 20.4 ± 16.1 | 16.4 ± 14.3 | 0.931 |
| FBTCS (# yes, %) | 4, 44.4% | 3, 60% | 7, 46.6% | 7, 63.6% | 3, 60% | 4, 57.1% | 0.872 |
| Seizure frequency (per month ± std) | 6.3 ± 7.7 | 17.9 ± 29.2 | 10.9 ± 9.3 | 42.5 ± 70.8 | 17.2 ± 26.7 | 8.0 ± 10.2 | 0.211 |
| MRI MTS (# yes, %) | 6, 66.6% | 3, 60% | 10, 66.6% | 5, 45.4% | 3, 60% | 4, 57.1% | 0.852 |
| PET lateralizing (# yes, %) | 7, 77.7% | 5, 100% | 13, 86.6% | 7, 63.6% | 3, 60% | 5, 71.4% | 0.562 |
| Ictal EEG lateralizing (# yes, %) | 9, 100% | 5, 100% | 13, 86.6% | 9, 81.8% | 4, 80% | 5, 71.4% | 0.932 |
| Interictal EEG lateralizing (# yes, %) | 6, 66.6% | 4, 80% | 11, 73.3% | 9, 81.8% | 4, 80% | 4, 57.1% | 0.682 |
| Invasive recording (SEEG) (# yes, %) | 0, 0% | 0, 0% | 3, 20% | 4, 36.3% | 0, 0% | 1, 14.2% | 0.412 |
| Type of surgery (selAH, TL, laser) | 5, 4, 0 | 4, 1, 0 | 13, 1, 1 | 10, 1, 0 | 3, 2, 0 | 3, 3, 1 | 0.152 |
std = standard deviation, Side = side of epileptogenic zone, F = females, # = number, % = percent of patients in the group (model, test, left-out), R = right, FBTCS = focal to bilateral tonic–clonic seizures, MTS = mesial temporal sclerosis on MRI, SEEG = stereo-electroencephalography, selAH = selective amygdalo-hippocampectomy, TL = temporal lobectomy, laser = laser ablation, 1 = Kruskal–Wallis test between outcomes of the left-out group, 2 = Chi-square test between outcomes of the left-out group, P is P-value of statistical test between four outcome groups of the left-out data set.