Table 3. Associations Between the Presence of Atherosclerosis in Individual Vascular Territories.
| Measure | Intracranial artery | Extracranial artery | Coronary artery | Subclavian artery | Aortic artery | Renal artery | Ilio-femoral artery | Ankle-brachial index ≤0.9 |
|---|---|---|---|---|---|---|---|---|
| Intracranial artery | ||||||||
| PPV, % | NA | 49.3 | 58.5 | 66.3 | 91.2 | 44.4 | 86.6 | 2.0 |
| NPV, % | NA | 66.3 | 58.0 | 53.7 | 22.8 | 74.7 | 26.5 | 98.5 |
| OR (95% CI)a | NA | 1.81 (1.50-2.20) | 1.61 (1.32-1.97) | 1.86 (1.51-2.29) | 2.42 (1.75-3.35) | 1.89 (1.54-2.33) | 1.79 (1.35-2.36) | 1.56 (0.79-3.12) |
| P value | NA | <.001 | <.001 | <.001 | <.001 | <.001 | <.001 | .20 |
| Extracranial artery | ||||||||
| PPV, % | 23.8 | NA | 50.6 | 59.8 | 85.3 | 38.0 | 82.0 | 2.0 |
| NPV, % | 86.0 | NA | 58.4 | 55.9 | 23.5 | 76.7 | 27.8 | 98.6 |
| OR (95% CI)a | 1.81 (1.50-2.20) | NA | 1.26 (1.08-1.47) | 1.74 (1.48-2.04) | 1.54 (1.26-1.90) | 1.99 (1.67-2.37) | 1.49 (1.22-1.81) | 1.55 (0.87-2.75) |
| P value | <.001 | NA | .004 | <.001 | <.001 | <.001 | <.001 | .13 |
| Coronary artery | ||||||||
| PPV, % | 22.8 | 40.9 | NA | 60.1 | 89.6 | 40.4 | 88.5 | 1.5 |
| NPV, % | 86.8 | 67.4 | NA | 58.6 | 28.5 | 80.8 | 34.6 | 98.3 |
| OR (95% CI)a | 1.61 (1.32-1.97) | 1.26 (1.08-1.47) | NA | 1.55 (1.32-1.81) | 2.37 (1.91-2.94) | 2.16 (1.82-2.58) | 2.78 (2.26-3.41) | 1.03 (0.56-1.88) |
| P value | <.001 | .004 | NA | <.001 | <.001 | <.001 | <.001 | .93 |
| Subclavian artery | ||||||||
| PPV, % | 23.5 | 43.6 | 54.1 | NA | 92.5 | 43.3 | 88.1 | 1.3 |
| NPV, % | 88.1 | 70.9 | 64.4 | NA | 33.6 | 85.8 | 36.3 | 98.1 |
| OR (95% CI)a | 1.86 (1.51-2.29) | 1.74 (1.48-2.04) | 1.55 (1.32-1.81) | NA | 4.56 (3.63-5.74) | 3.52 (2.92-4.24) | 2.91 (2.38-3.55) | 0.86 (0.47-1.58) |
| P value | <.001 | <.001 | <.001 | NA | <.001 | <.001 | <.001 | .62 |
| Aortic artery | ||||||||
| PPV, % | 20.2 | 38.8 | 50.6 | 58.0 | NA | 34.5 | 84.8 | 1.7 |
| NPV, % | 92.4 | 73.8 | 77.0 | 81.9 | NA | 94.0 | 59.1 | 98.5 |
| OR (95% CI)a | 2.42 (1.75-3.35) | 1.54 (1.26-1.90) | 2.37 (1.91-2.94) | 4.56 (3.63-5.74) | NA | 6.06 (4.26-8.62) | 5.53 (4.50-6.81) | 1.48 (0.70-3.16) |
| P value | <.001 | <.001 | <.001 | <.001 | NA | <.001 | <.001 | .31 |
| Renal artery | ||||||||
| PPV, % | 27.3 | 48.1 | 63.2 | 75.2 | 95.8 | NA | 94.4 | 1.5 |
| NPV, % | 86.3 | 68.5 | 62.5 | 60.4 | 26.9 | NA | 31.7 | 98.3 |
| OR (95% CI)a | 1.89 (1.54-2.33) | 1.99 (1.67-2.37) | 2.16 (1.82-2.58) | 3.52 (2.92-4.24) | 6.06 (4.26-8.62) | NA | 5.91 (4.31-8.10) | 1.16 (0.58-2.29) |
| P value | <.001 | <.001 | <.001 | <.001 | <.001 | NA | <.001 | .68 |
| Iliofemoral artery | ||||||||
| PPV, % | 20.1 | 39.4 | 52.4 | 57.8 | 89.0 | 35.7 | NA | 1.6 |
| NPV, % | 90.2 | 73.1 | 78.7 | 75.4 | 49.9 | 93.4 | NA | 98.4 |
| OR (95% CI)a | 1.79 (1.35-2.36) | 1.49 (1.22-1.81) | 2.78 (2.26-3.41) | 2.91 (2.38-3.55) | 5.53 (4.50-6.81) | 5.91 (4.31-8.10) | NA | 1.33 (0.66-2.68) |
| P value | <.001 | <.001 | <.001 | <.001 | <.001 | <.001 | NA | .43 |
| Ankle-brachial index ≤0.9 | ||||||||
| PPV, % | 22.4 | 44.9 | 40.8 | 41.7 | 81.6 | 26.5 | 75.5 | NA |
| NPV, % | 82.3 | 63.7 | 55.0 | 50.1 | 20.4 | 71.3 | 24.2 | NA |
| OR (95% CI)a | 1.56 (0.79-3.12) | 1.55 (0.87-2.75) | 1.03 (0.56-1.88) | 0.86 (0.47-1.58) | 1.48 (0.70-3.16) | 1.16 (0.58-2.29) | 1.33 (0.66-2.68) | NA |
| P value | .20 | .13 | .93 | .62 | .31 | .68 | .43 | NA |
Abbreviations: OR, odds ratio; NA, not applicable; NPV, negative predictive value; PPV, positive predictive value.
a
ORs were calculated using logistic regression models with presence of atherosclerosis in the artery in the column title (eg, extracranial artery) as the dependent variable and presence of atherosclerosis in the artery of the row title (eg, intracranial artery) as the independent variable, adjusted for age and sex.