Table 2.
Inclusion | Adults 18–65 years |
Diagnosed with IBS-D or IBS-M according to the rome IV criteria | |
Expected adherence to following the protocol | |
Written consent to the study | |
Exclusion | The use of antibiotics and probiotics within 1 month prior to faecal microbiota transplantation |
History of inflammatory bowel disease or gastrointestinal malignancy, systemic autoimmune diseases (ongoing or in history) | |
Previous abdominal surgery (other than appendectomy or cholecystectomyor hernioplasty or caesarean section) | |
HIV infection or other active infection | |
Renal or hepatic disease (both defined by biochemistry workup) | |
Diabetes mellitus, abnormal thyroid functions not controlled by thyroid medications | |
Bipolar disorder or schizophrenia (ongoing or history thereof), moderately severe depression defined by Patient Health Questionnaire-9 score >15 | |
Anxiety defined by a Generalised Anxiety Disorder 7 score >10, with any organic causes that can explain the symptoms of IBS | |
Current pregnancy and lactation |
FMT, faecal microbiota transplantation; IBS, irritable bowel syndrome.