Table 3.

Study timeline for paediatric and adolescent patients with inflammatory bowel diseases

Time point	Time of diagnosis	During years 1–2 after diagnosis: Follow-up minimum every third month and at events	At 12 months of follow-up	During years 3–5 year after diagnosis: Follow-up minimum every 6 months and at events	60 months of follow-up	Years 6–20 Follow-up minimum annually and at events
Screening for inclusion	X
Participant information and written informed consent (repeated at age 18)	X
Collection of information from medical record including any medical adverse events	X	X	X	X	X	X
Impact III questionnaire	X	X	X	X	X
Detailed environmental questionnaire	X				X
Clinical disease activity	X	X	X	X	X
Collection of faecal samples	X	X	X	X	X
Collection of blood sample	X	X	X	X	X
Collection of biopsies at endoscopy	X	(X)	X	(X)	(X)
Collection of saliva sample	X	X	X	X	X
MR cholangio-pancreatography		(X)			(X)
MR enterography	X		X		X
Rheumatological assessment	X		(X)		X
Dermatological assessment	(X)	(X)	(X)	(X)	(X)
Left-hand radiograph for bone age	X		X
DXA scan	X				X
IUS	X	(X)	X		X
Collection of dental treatment needs	X	X	X	X	X	X

(X) indicates that the investigation will be performed if clinically relevant.

DXA, dual-energy X-ray absorptiometry; IUS, intestinal ultrasound.