Fig. 3.

dBET1 reduces infarct volume after stroke. A Representative images of TTC stained 1-mm thick coronal brain slices of vehicle- and dBET1-treated mice at 48 h after tMCAO. Quantitative analyses of the overall infarct volume (B) or detailed infarct area of each brain slice (C) were performed. The cortex, striatum, and hemisphere infarct volumes B were significantly reduced in the dBET1 group than the vehicle-treated control group. Analysis of infarct area per slice shows that the decreases in infarct volume are seen throughout the hemisphere. Veh: n = 14; dBET1: n = 13. *P < 0.05, **P < 0.01. Veh, vehicle; TTC, 2,3,5-triphenyl-2H-tetrazolium chloride