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. 2022 Jun 27;20:98. doi: 10.1186/s12964-022-00907-2

Fig. 4.

Fig. 4

Pyroptosis is activated in the lung tissues of mice infected with A. fumigatus after irradiation. a Representative western blot images showing changes in the levels of caspase 1-p20, gasdermin D (GSDMD-N), interleukin 18 (IL-18), IL-1β cleaved, b–e and their statistical results. f–i mRNA expression of ASC, NLRP3, NLRC4, and AIM2. j, k Secretion of IL-18 and IL-1β in BALF. Data are shown as the mean ± standard deviation (n = 8). *P < 0.05, **P < 0.01 versus the control group