Table I.

Remission key messages

Remission is an achievable and desirable target in SLE and a part of the treat-to-target strategy which can be applied in clinical practice

Optimally expressed remission guaranteeing the patient reduced mortality, prolonged time to next flare and the most important no organ damage

Chronic GCs therapy is a major independent predictor organ damage accrual. The principle of lupus treatment for rheumatologists should be minimizing or consider withdrawing GCs treatment

The final recommendations 2021 constitute a summary and consensus on a definition of remission in SLE – DORIS remission

Lupus low disease activity state is alternative target which is a compromise between achievable therapeutic effects and minimizing GCs doses