Table 1.
Characteristics of Study Population, Stratified by Quintiles of Age
| Characteristic | All* | Quintile 1 | Quintile 2 | Quintile 3 | Quintile 4 | Quintile 5 | P value |
|---|---|---|---|---|---|---|---|
| No. | 908 | 182 | 181 | 182 | 181 | 182 | |
| Age, mean (SD), y | 66.1 (13.3) | 45.6 (8.1) | 59.7 (3.0) | 68.4 (2.0) | 74.5 (1.8) | 82.1 (3.4) | <0.001 |
| Women, n (%) | 411 (45.3) | 66 (36.3) | 82 (45.3) | 86 (47.3) | 92 (50.8) | 85 (46.7) | 0.07 |
| Hypertension, n (%) | 442 (48.7) | 40 (22.0) | 73 (40.3) | 96 (52.7) | 109 (60.2) | 124 (68.1) | <0.001 |
| Diabetes, n (%) | 107 (11.8) | 19 (10.4) | 22 (12.2) | 18 (9.9) | 24 (13.3) | 24 (13.2) | 0.79 |
| Current smoking, n (%) | 152 (16.7) | 60 (33.0) | 43 (23.8) | 28 (15.4) | 12 (6.6) | 9 (4.9) | <0.001 |
| Antihypertensive agents, n (%) | 670 (73.8) | 98 (53.8) | 117 (64.6) | 148 (81.3) | 153 (84.5) | 154 (84.6) | <0.001 |
| BMI, mean (SD), kg/m2 | 27.2 (5.3) | 27.9 (6.6) | 28.5 (5.5) | 26.7 (4.9) | 26.5 (4.2) | 26.2 (4.5) | <0.001 |
| SBP, mean (SD), mm Hg | 125.4 (18.0) | 119.3 (15.8) | 121.0 (13.8) | 127.6 (18.3) | 128.9 (18.5) | 130.3 (20.1) | <0.001 |
| DBP, mean (SD), mm Hg | 68.8 (10.0) | 70.8 (10.5) | 70.9 (9.2) | 68.7 (10.3) | 68.0 (9.4) | 65.5 (9.9) | <0.001 |
| PP, mean (SD), mm Hg | 56.6 (14.8) | 48.5 (11.8) | 50.1 (11.2) | 58.9 (13.5) | 61.0 (13.9) | 64.7 (16.3) | <0.001 |
| PWV, mean (SD), m/s | 9.6 (2.7) | 7.5 (1.7) | 8.5 (1.8) | 9.7 (2.1) | 10.6 (2.5) | 12.1 (3.0) | <0.001 |
Frequency, number (percentage), or mean (SD) are reported. P values are given for ANOVA for continuous variables and χ2 test for categorical variables. Quintile 1 indicates <54.2 years; quintile 2, 54.2 to 64.7 years; quintile 3, 64.7 to 71.4 years; quintile 4, 71.4 to 77.7 years; and quintile 5, >77.7 years. BMI indicates body mass index; DBP, diastolic blood pressure; PP, pulse pressure; PWV, pulse wave velocity; and SBP, systolic blood pressure.
*
One patient with missing diagnosis of all comorbidities; 93 patients did not have PWV assessed; 2 patients with missing information of antihypertensive agents; and 63 patients with missing information of BMI.