Figure 6. Circulating DNA dynamics and patient characteristics most important to accurately determine preeclampsia diagnosis via elastic net penalized regression.
A, Subject characteristics whose variable importance probabilities (VIP) reached at least 75%. B, Adjusted odds ratios (OR) of selected subject characteristics. Vertical line represents OR=1 (no effect); horizontal line represents VIP 0.75 cutoff. BMI, body mass index; MAP, mean arterial pressure; mtDNA, mitochondrial DNA; nDNA, nuclear DNA; NOB, time of first (new) obstetric appointment.