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. 2022 Jan 13;11(2):e021188. doi: 10.1161/JAHA.121.021188

Figure 3. In vitro treatment of plasma with DNase 1 lowered age‐associated increase in thrombin generation potential in mice regardless of genotype.

Figure 3

Platelet poor plasma from young and aged wild‐type mice or glutathione peroxidase‐1 transgenic (Gpx1 Tg) littermates were treated with either 20 µg/mL of DNase 1 or same dose of heat‐inactivated DNase 1 as control for 60 minutes, and thrombin generation (endogenous thrombin potential [ETP]) was measured. Data are expressed as mean±SD. Three‐way ANOVA with Šídák's multiple comparisons. N=5 to 7 in each group.