Table 1.
Clinical characteristics |
Total (n=7065) |
VIM quartile 1 (n=1766) |
VIM quartile 2 (n=1767) |
VIM quartile 3 (n=1766) |
VIM quartile 4 (n=1766) |
P value |
---|---|---|---|---|---|---|
Age, y | 59.3 (5.6) | 59.1 (5.6) | 59.3 (5.4) | 59.2 (5.7) | 59.5 (5.5) | 0.137 |
Sex | <0.001 | |||||
Men | 3129 (44.3) | 873 (49.4) | 816 (46.2) | 755 (42.8) | 685 (38.8) | |
Women | 3936 (55.7) | 893 (50.6) | 951 (53.8) | 1011 (57.2) | 1081 (61.2) | |
Race | 0.001 | |||||
Black | 1207 (17.1) | 272 (15.4) | 276 (15.6) | 307 (17.4) | 352 (19.9) | |
White | 5858 (82.9) | 1494 (84.6) | 1491 (84.4) | 1459 (82.6) | 1414 (80.1) | |
Body mass index, kg/m2 | 27.9 (5.1) | 28.0 (5.1) | 27.7 (4.9) | 27.9 (5.1) | 28.1 (5.4) | 0.181 |
SBP, mm Hg | 117.2 (11.4) | 115.3 (11.0) | 115.9 (10.9) | 117.6 (11.1) | 120.2 (11.4) | <0.001 |
Diastolic BP, mm Hg | 69.9 (8.7) | 69.6 (8.5) | 69.3 (8.5) | 70.0 (8.9) | 70.5 (8.9) | <0.001 |
Total cholesterol, mmol/L | 5.4 (1.0) | 5.4 (0.9) | 5.3 (1.0) | 5.4 (1.0) | 5.4 (1.0) | 0.893 |
HDL‐C, mmol/L | 1.4 (0.5) | 1.3 (0.4) | 1.4 (0.5) | 1.4 (0.5) | 1.4 (0.5) | <0.001 |
LDL‐C, mmol/L | 3.3 (0.9) | 3.3 (0.9) | 3.3 (0.9) | 3.3 (0.9) | 3.2 (0.9) | 0.158 |
Triglyceride, mmol/L | 1.6 (0.9) | 1.6 (0.9) | 1.6 (0.9) | 1.6 (1.0) | 1.6 (0.9) | 0.969 |
Diabetes | 794 (11.2) | 207 (11.7) | 196 (11.1) | 189 (10.7) | 202 (11.4) | 0.794 |
Hypertension, n (%) | 1718 (24.3) | 391 (22.1) | 376 (21.3) | 418 (23.7) | 533 (30.2) | <0.001 |
Atrial fibrillation | 17 (0.2) | 3 (0.2) | 3 (0.2) | 5 (0.3) | 6 (0.3) | 0.659 |
Education level | 0.019 | |||||
Basic or 0 y | 1138 (16.1) | 263 (14.9) | 262 (17.3) | 306 (17.3) | 307 (17.4) | |
Intermediate | 3005 (42.5) | 774 (43.8) | 733 (41.5) | 723 (40.9) | 775 (43.9) | |
Advanced | 2922 (41.4) | 729 (41.3) | 772 (43.7) | 737 (41.7) | 684 (38.7) | |
Smoking | 0.034 | |||||
Current smoker | 1237 (17.5) | 279 (15.8) | 290 (16.4) | 318 (18.0) | 350 (19.8) | |
Former smoker | 2878 (40.7) | 738 (41.8) | 742 (42.0) | 694 (39.3) | 704 (39.9) | |
Never smoker | 2950 (41.8) | 749 (42.4) | 735 (41.6) | 754 (42.7) | 712 (40.3) | |
Drinking | 0.006 | |||||
Current drinker | 3985 (56.4) | 1065 (60.3) | 1001 (56.6) | 957 (54.2) | 962 (54.5) | |
Former drinker | 1441 (20.4) | 316 (17.9) | 362 (20.5) | 382 (21.6) | 381 (21.6) | |
Never drinker | 1639 (23.3) | 385 (21.8) | 404 (22.9) | 427 (24.2) | 423 (24.0) | |
Antihypertensive | 1664 (23.6) | 376 (21.3) | 367 (20.8) | 403 (22.8) | 518 (29.3) | <0.001 |
Aspirin | 3566 (50.5) | 854 (48.4) | 889 (50.3) | 895 (50.7) | 928 (52.5) | 0.100 |
Statin | 301 (4.3) | 70 (4.0) | 76 (4.3) | 72 (4.1) | 83 (4.7) | 0.713 |
Continuous variables are presented as mean (SD), and categorical variables are presented as percentage. HDL‐C indicates high density lipoprotein cholesterol; LDL‐C, low density lipoprotein cholesterol; SBP, systolic blood pressure; and VIM, variability independent of the mean.