Figure 4. The 5‐year incremental net monetary benefit of pooled cohort equation (PCE) alone vs PCE+polygenic risk score for coronary artery disease (CAD‐PRS), with PCE+CAD‐PRS preferred across all parameter value variations except when the annual risk of developing CAD was <0.006.

CAD indicates coronary artery disease; EV, expected value; and PRS, polygenic risk score.