Table 2.
Clinical Data and Outcomes for Patients With Anterior Circulation Large‐Vessel Occlusion Undergoing EVT
| DCR (−) (N=62) | DCR (+) (N=38) | P value | Poor outcome (N=57) | Good outcome (N=43) | P value | |
|---|---|---|---|---|---|---|
| Demographics | ||||||
| Sex (female), n (%) | 11 (17.74) | 9 (23.68) | 0.607 | 8 (14.04) | 12 (31.58) | 0.129 |
| Age, y, mean (SD) | 62.85±10.80 | 63.29±10.73 | 0.845 | 62.98±11.18 | 63.07±10.22 | 0.968 |
| Hypertension, n (%) | 38 (61.29) | 26 (68.42) | 0.666 | 35 (61.40) | 29 (67.44) | 0.675 |
| Diabetes, n (%) | 20 (32.26) | 8 (21.05) | 0.259 | 22 (38.60) | 6 (13.95) | 0.007 |
| Atrial fibrillation, n (%) | 20 (32.26) | 12 (31.58) | 0.562 | 15 (26.32) | 17 (39.53) | 0.196 |
| Stroke, n (%) | 16 (25.81) | 11 (28.95) | 0.818 | 15 (26.32) | 12 (27.90) | 0.859 |
| Smoking story, n (%) | 34 (54.84) | 24 (63.16) | 0.532 | 35 (61.40) | 23 (53.49) | 0.540 |
| Clinical and imaging features | ||||||
| Admission NIHSS, mean (SD) | 15.56±4.75 | 15.89±4.05 | 0.722 | 16.65±4.66 | 14.42±3.03 | 0.011 |
| ASPECTS, median (IQR) | 9 (7–10) | 9 (8–10) | 0.636 | 8 (6.5–10) | 9 (8–10) | 0.062 |
| SBP after EVT, mean (SD) | 138.03±22.48 | 142.47±25.81 | 0.362 | 141.77±23.18 | 137.00±23.95 | 0.318 |
| DBP after EVT, mean (SD) | 81.13±13.60 | 84.87±16.31 | 0.219 | 83.52±14.48 | 81.55±13.74 | 0.834 |
| sCCT, s, median (IQR) |
2.33 (1.83–3.33) |
2.00 (1.67–2.33) |
0.009 |
2.33 (1.83–3.42) |
2.00 (1.67–2.33) |
0.015 |
| hCCT, s, median (IQR) |
2.17 (1.79–2.83) |
2.33 (1.67–2.71) |
0.946 |
2.17 (1.75–2.83) |
2.00 (1.67–2.67) |
0.859 |
| cCCT, median (IQR) |
0.13 (−0.08 to 0.38) |
−0.12 (−0.31 to 0.16) |
0.005 |
0.15 (−0.07 to 0.42) |
−0.10 (−0.17 to 0.14) |
0.003 |
| Collateral score, median (IQR) | 1 (0–2) | 2 (1–3) | 0.008 | 1 (0–2) | 2 (1–3) | 0.005 |
| Number of passes, median (IQR) | 2 (1–2) | 1 (1–2) | 0.014 | 2 (1–2) | 1 (1–2) | 0.041 |
| NRV stenosis, n (%) | 33 (53.23) | 19 (50.00) | 0.838 | 29 (50.88) | 23 (53.49) | 0.842 |
| OPT, min, median (IQR) |
317 (238–477) |
407 (225–751) |
0.369 |
374 (250–532) |
329 (229–451) |
0.347 |
| DPT, min, median (IQR) | 49 (36–79) | 53 (33–106) | 0.572 | 55 (41–98) | 46 (29–82) | 0.077 |
| ORT, min, median (IQR) |
436 (318–593) |
397 (319–655) |
0.915 |
487 (322–629) |
372 (311–576) |
0.204 |
| Final mTICI | 0.407 | 0.102 | ||||
| mTICI 2B, n (%) | 29 (46.77) | 14 (36.84) | 29 (50.88) | 14 (32.56) | ||
| mTICI 3, n (%) | 33 (53.23) | 24 (63.16) | 28 (49.12) | 29 (67.44) | ||
| TOAST, n (%) | 0.428 | 0.709 | ||||
| LAA | 35 (56.45) | 25 (65.79) | 36 (63.18) | 24 (55.81) | ||
| Cardioembolism | 19 (30.65) | 7 (18.42) | 13 (22.81) | 13 (30.23) | ||
| Undetermined | 8 (12.90) | 6 (15.79) | 8 (14.04) | 6 (13.95) | ||
| ICH | 30 (48.39) | 11 (28.95) | 0.063 | 29 (50.88) | 12 (27.91) | 0.025 |
| ICH type, n (%) | 0.408 | 0.046 | ||||
| HI‐1 | 3 (4.84) | 1 (2.63) | 1 (1.75) | 3 (6.98) | ||
| HI‐2 | 6 (9.68) | 3 (7.89) | 7 (12.28) | 2 (4.65) | ||
| PH‐1 | 6 (9.68) | 1 (2.63) | 6 (10.53) | 1 (2.32) | ||
| PH‐2 | 15 (24.19) | 6 (15.79) | 15 (26.32) | 6 (13.95) | ||
ASPECTS indicates Alberta Stroke Program Early CT Score; cCCT, the change of sCCT versus hCCT; CCT, cerebral circulation time; DBP, diastolic blood pressure; DCR, dramatic clinical recovery; DPT, door‐to‐puncture time; EVT, endovascular treatment; HI‐1, hemorrhagic infarction‐1； HI‐2, hemorrhagic infarction‐2; hCCT, CCT of the contralateral healthy side; ICH, intracranial hemorrhage; IQR, interquartile range; LAA, large artery atherosclerosis; mTICI, modified Thrombolysis in Cerebral Ischemia; NIHSS, National Institutes of Health Stroke Scale; NRV stenosis, non‐responsible vessel stenosis; OPT, onset‐to‐puncture time; ORT, onset‐to‐reperfusion time; PH‐1, parenchymal hematona‐1; PH‐2, parenchymal hematona‐2; SBP, systolic blood pressure; sCCT, CCT of the stroke ipsilateral to the side; and TOAST, Trial of Org 10172 in Acute Stroke Treatment.