Table 2.
Adjusted Odds Ratio of CAC or ECC>100 Comparing Elevated Lp(a) to Normal Lp(a)
| Lp(a) ≤50 mg/dL | Lp(a) >50 mg/dL | |
|---|---|---|
| CAC | ||
| Model 1 | Reference | 0.98 (0.78–1.23) |
| Model 2 | Reference | 1.40 (1.08–1.81) |
| Model 3 | Reference | 1.35 (1.04–1.75) |
| Thoracic Aorta | ||
| Model 1 | Reference | 1.06 (0.83–1.34) |
| Model 2 | Reference | 1.36 (1.05–1.77) |
| Model 3 | Reference | 1.35 (1.04–1.76) |
| Aortic valve | ||
| Model 1 | Reference | 1.36 (1.04–1.79) |
| Model 2 | Reference | 1.82 (1.34–2.47) |
| Model 3 | Reference | 1.79 (1.32–2.43) |
| Aortic valve ring | ||
| Model 1 | Reference | 1.18 (0.95–1.47) |
| Model 2 | Reference | 1.36 (1.07–1.73) |
| Model 3 | Reference | 1.32 (1.04–1.67) |
| Mitral valve | ||
| Model 1 | Reference | 1.23 (0.96–1.57) |
| Model 2 | Reference | 1.37 (1.06–1.78) |
| Model 3 | Reference | 1.35 (1.04–1.76) |
Model 1 is unadjusted.
Model 2 is adjusted for age, race, sex, education level, smoking status, alcohol drinking status, and cardiometabolic risk factors (body‐mass index, systolic blood pressure, diabetes, antihypertensive medication use, high‐density lipoprotein cholesterol, and triglycerides).
Model 3 is Model 2 + lipid lowering therapy. CAC indicates coronary artery calcium; ECC, extracoronary calcification; and Lp(a), lipoprotein(a).