FIG 5.

S. hominis synthetic AIPs inhibit S. epidermidis agr signaling. (A to E) S. epidermidis P3::sGFP reporters were incubated with increasing doses of S. hominis synthetic AIP-I (A), AIP-II (B), AIP-III (C), AIP-IV (D), or AIP-V (E). Fluorescent intensity relative to the reporter only at the 24-h time point is shown. (F) IC₅₀ values (nM) were calculated for each AIP-reporter pair from a four-parameter nonlinear regression curve. The 95% confidence interval for each IC₅₀ value is reported in parentheses. Results are pooled from three independent experiments. Mean ± SD values are shown. NC, not calculated.