TABLE 2.
MICs (μg/mL) of β-lactams against A. baumannii clinical isolates
| Enzymea | Antibiotic MICs (μg/mL) |
No. of strains | ||
|---|---|---|---|---|
| Imipenem | Meropenem | MA-1-206 | ||
| OXA-23 | 16–64 | 32–128 | 8–16 | 22 |
| OXA-23, OXA-24/40 | 64 | 128 | 16 | 1 |
| OXA-24/40 | 64–128 | 128–256 | 32–64 | 8 |
| OXA-58 | 8 | 8 | 8 | 2 |
| OXA-72 | 64–128 | 256–512 | ≥128 | 8 |
| NDM-1 | 64–256 | 128–512 | ≥128 | 3 |
| NDM-1, OXA-23 | 128 | 256 | ≥128 | 1 |
All strains encode OXA-51 (such as OXA-65, -66, -69, -82, -94, -100, -203, and -223) and ADC derivatives. Twenty strains encode TEM-type and two encode PER-7 β-lactamases.