FIG 4.
Antibiotic treatment sensitizes mice to S. aureus bloodstream infection. (A to C) Survival curves of antibiotic-treated C57BL/6J mice infected intravenously (i.v.) with 1 × 107 CFU of LAC (A), TH16 (B), and BS_4884 (C) (n = 5 to 15 mice/group). (D and E) Bacterial burdens of intravenously infected mice 24 h after infection with LAC (D) and TH16 (E) (n = 7 to 18 mice/group) (means ± SEM). Statistical analysis was performed using a log rank (Mantel-Cox) test (A to C) and two-way ANOVA with a Šídák posttest (D and E). *, P < 0.05; ***, P < 0.001.