FIG 6.
Pathogen and host protein biomarkers that are predictive of outcomes at admission. (A) Box plots of CT values (P value = 0.17) and EBV GP (P value = 0.17) expression levels segregated according to patient outcomes (survival or fatality). Both pathogen biomarkers have similar profiles, with an area under the receiver operating characteristic curve (AUROC) value of 0.75 (circles, CT values; squares, EBV GP). (B) Box plots of H1-5, RPL35, MSN, and KNG1 protein expression levels at admission, segregated according to patient outcomes. Each host biomarker protein identified has an AUROC value of 1.00, with a value of 1.00 being perfect accuracy (P value = 0.0027 for H1.5, P value = 0.0019 for MSN, and P value = 0.0019 for KNG1) (n = 12) (survivors are in purple; fatalities are in orange).