TABLE 2.

Summary of plasmids and passages diversities of DV2 directed evolution

Plasmid or passage (P)	C6/36 evolved		Vero evolved
	No. of unique sequences	% maximum	No. of unique sequences	% maximum
Plasmid	164,569	102.86*	164,569	102.86*
P1	25,942	16.21	1,148	0.72
P2	14,119	8.82	719	0.45
P3	6,026	3.77	683	0.43

*, Including stop codons.