TABLE 2.

Highest-Scoring SNPs

					PROVIDE		CBC		Meta-Analysis
rsID	Chr:Posa	A0a	A1a	Pop MAFa	OR (95% CI)	P valueb	OR (95% CI)	P valueb	Case MAF	Control MAF	OR (95% CI)	P valuec	Phet a
rs13281104	8:1811923	Ad	G	0.16	0.45 (0.30, 0.67)	9.6 × 10−5	0.35 (0.19, 0.65)	8.6 × 10−4	0.12	0.24	0.41 (0.29, 0.58)	3.6 × 10−7	0.52
rs13272734	8:1817756	Cd	G	0.17	0.46 (0.31, 0.69)	1.6 × 10−4	0.37 (0.20, 0.68)	1.3 × 10−3	0.12	0.24	0.43 (0.31, 0.60)	9.1 × 10−7	0.54
rs7003839	8:1817314	Gd	C	0.17	0.46 (0.31, 0.69)	1.7 × 10−4	0.37 (0.20, 0.69)	1.6 × 10−3	0.12	0.24	0.44 (0.31, 0.61)	1.1 × 10−6	0.56
rs13277141	8:1815147	Gd	C	0.18	0.46 (0.31, 0.68)	8.5 × 10−5	0.41 (0.22, 0.75)	3.9 × 10−3	0.13	0.25	0.45 (0.32, 0.62)	1.1 × 10−6	0.75
rs13252399	8:1815012	Td	A	0.17	0.47 (0.31, 0.70)	1.9 × 10−4	0.37 (0.20, 0.68)	1.5 × 10−3	0.12	0.24	0.44 (0.31, 0.61)	1.2 × 10−6	0.54
rs13267804	8:1813692	Cd	T	0.17	0.47 (0.31, 0.69)	1.7 × 10−4	0.38 (0.21, 0.70)	1.8 × 10−3	0.12	0.24	0.44 (0.31, 0.61)	1.2 × 10−6	0.58
rs17829629e	8:1817961	C	Ad	0.15	0.47 (0.31, 0.70)	1.9 × 10−4	0.38 (0.21, 0.71)	2.3 × 10−3	0.12	0.23	0.44 (0.31, 0.61)	1.7 × 10−6	0.60

^aChr, chromosome; Pos, position; A0, reference allele; A1, tested allele; Pop MAF, minor allele frequency reported in 1000 Genomes for the Bengali in Bangladesh population; OR, odds ratio; CI, confidence interval; P_het, P value of heterogeneity from Cochran’s Q.

^bP value from frequentist association test.

^cP value from the meta-analysis.

^dAncestral allele.

^eGenotyped SNP.