TABLE 1.

Extracellular virulence factors of A. actinomycetemcomitans significantly or uniquely associated with virulence in different infection models

Infection model	Protein name
Larval melanization	Pilus assembly protein N-terminal domain-containing protein RcpA
Larval survival	Pilus assembly protein N-terminal domain-containing protein RcpC
	Poly-beta-1,6-N-acetyl-d-glucosamine N-deacetylase PgaB
	Oligopeptide ABC transporter substrate-binding protein OppA
Epithelial cell killing	Chaperonin GroEL
	TolC family protein
Neutrophil killing/NETosis	Do family serine endopeptidase DegP
	Flp pilus assembly protein TadE
	Flp pilus assembly protein TadF
	Flp pilus assembly protein TadG