FIG 5.

Status of expression of cytokines by CD4⁺ and CD8⁺ memory T cells following CoronaVac vaccination. (A) Example flow cytometry gating strategy. (B to M) Percentages of CD4⁺ T_CM, CD4⁺ T_EM, CD8⁺ T_EM, and CD8⁺ T_E cells expressing IFN-γ (B to E), IL-2 (F to I), and GrzB (J to M) that responded specifically to RBD stimulation. The error bars are the geometric mean with 95% CI. A Wilcoxon matched-pair signed rank test was used for x. Two-sided P values are shown. IFN, interferon; IL, interleukin. T_CM, central memory T cells; T_EM, effector memory T cells; T_E, terminal effector T cells.