4. Full‐mouth disinfection versus control: change in probing pocket depth.

Tooth type: single‐ or multi‐rooted, or both	Baseline pocket depth (mm)	Time (months)	Number of studies (participants)	Mean difference (95% CI) (random‐effects meta‐analysis)	Heterogeneity
Both	5–6	3/4	2 (56)	0.50 (–0.33, 1.33); P = 0.24	P = 0.02; I² = 83%
Both	> 6	3/4	3 (72)	0.32 (–1.22, 1.85); P = 0.69	P < 0.0001; I² = 91%
Both	5–6	6/8	1 (28)	0.88 (0.20, 1.56); P = 0.01	Not applicable
Both	> 6	6/8	2 (44)	–0.10 (–0.47, 0.26); P = 0.58	P = 0.46; I² = 0%
Single‐rooted	5–6	3/4	3 (50)	0.28 (–0.59, 1.15); P = 0.52	P = 0.0005; I² = 87%
Single‐rooted	> 6	3/4	2 (34)	1.28 (–0.48, 3.04); P = 0.15	P = 0.03; I² = 78%
Single‐rooted	5–6	6/8	5 (103)	0.41 (0.11, 0.70); P = 0.006	P = 0.01; I² = 70%
Single‐rooted	> 6	6/8	4 (87)	0.78 (–0.01, 1.57); P = 0.05	P = 0.03; I² = 67%
Multi‐rooted	5–6	3/4	3 (50)	0.18 (–0.79, 1.15); P = 0.72	P = 0.003; I² = 83%
Multi‐rooted	> 6	3/4	2 (34)	1.28 (0.44, 2.11); P = 0.003	P = 0.92; I² = 0%
Multi‐rooted	5–6	6/8	5 (103)	0.21 (–0.12, 0.53); P = 0.21	P = 0.03; I² = 62%
Multi‐rooted	> 6	6/8	4 (87)	0.56 (–0.23, 1.34); P = 0.16	P = 0.04; I² = 65%

CI: confidence interval.