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. 2022 Jun 28;2022(6):CD004622. doi: 10.1002/14651858.CD004622.pub4

5. Full‐mouth disinfection versus control: change in clinical attachment level.

Tooth type:
single‐ or multi‐rooted,
or both Baseline pocket depth (mm) Time
(months) Number of studies (participants) Mean difference (95% CI)
(random‐effects meta‐analysis) Heterogeneity
Both 5–6 3/4 1 (28) 0.18 (–0.21, 0.57); P = 0.37 Not applicable
Both > 6 3/4 2 (44) –0.39 (–1.32, 0.54); P = 0.42 (P = 0.06); I² = 71%
Both 5–6 6/8 0 (0) Not estimable Not applicable
Both > 6 6/8 1 (16) –0.16 (–0.41, 0.09); P = 0.20 Not applicable
Single‐rooted 5–6 3/4 2 (40) 0.08 (–0.87, 1.04); P = 0.86 (P = 0.04); I² = 75%
Single‐rooted > 6 3/4 1 (24) 1.90 (0.73, 3.07); P = 0.001 Not applicable
Single‐rooted 5–6 6/8 3 (64) 0.14 (0.00, 0.28); P = 0.05 (P = 0.48); I² = 0%
Single‐rooted > 6 6/8 2 (48) 0.72 (–0.94, 2.37); P = 0.40 (P = 0.03); I² = 79%
Multi‐rooted 5–6 3/4 2 (40) 0.27 (–1.21, 1.75); P = 0.72 (P = 0.001); I² = 90%
Multi‐rooted > 6 3/4 1 (24) 1.30 (0.20, 2.40); P = 0.02 Not applicable
Multi‐rooted 5–6 6/8 3 (64) 0.12 (–0.17, 0.41); P = 0.43 (P = 0.07); I² = 62%
Multi‐rooted > 6 6/8 2 (48) 0.52 (–1.30, 2.34); P = 0.57 (P = 0.005); I² = 87%

CI: confidence interval.