11. Pocket closure.

a Study	Outcome	Category of PD included for evaluation	Results
Afacan 2020	Control, FMS, FMD	Percentage of PPD ≥ 5 mm; before and after treatment	No difference between groups, significant reductions in all groups.
Apatzidou 2004	Control, FMS	Number of sites with PPD > 5 mm; before and after treatment	No difference between groups, significant reductions in both groups.
Babaloo 2018	Pocket closure was not a planned outcome.
Del Peloso 2008	Pocket closure was not a planned outcome.
Fonseca 2015	Control, FMS, FMD	Percentage of periodontal diseased sites ('PDS': sites with PD ≥ 4 mm and CAL ≥ 3 mm); before and after treatment	No difference between groups, significant reductions in all groups.
Graziani 2015	Control, FMS	Number of pockets with PPD > 4 mm before and after treatment	No differences between groups, there was a reduction in number and percentage of pockets with PPD ≤ 4 mm after therapy in both groups.
Jervøe‐Storm 2006	Control, FMS	Proportions of sites with PPD ≤ 4 mm before and after treatment	No differences between groups, there was an increase of sites with PPD ≤ 4 mm after therapy in both groups, with a slightly higher proportion in the FMS group.
Koshy 2005	Control, FMS, FMD	Reduction in number of sites ≥ 5 mm; before and after treatment	The number of pocket sites (≥ 5 mm) reduced significantly in all 3 groups 6 months after treatment, with greater reduction observed in both full‐mouth groups compared with the control group.
Mongardini 1999	Pocket closure was not a planned outcome.
Pontillo 2018	Pocket closure was not a planned outcome.
Predin 2014	Pocket closure was not a planned outcome.
Quirynen 2006	Pocket closure was not a planned outcome.
Roman‐Torres 2018	Pocket closure was not a planned outcome.
Santuchi 2015	Control, FMD	Percentage of sites with PD 5–6 mm; before and after treatment	No difference between groups, significant reductions in both groups.
Soares 2015	Pocket closure was not a planned outcome.
Swierkot 2009	Pocket closure was not a planned outcome.
Vandekerckhove 1996	Pocket closure was not a planned outcome.
Wennström 2005	Control, FMS	Proportions of sites with PPD ≤ 4 mm before and after treatment	No differences between both groups, proportion of pockets with PPD ≤ 4 increased in both groups. QRP showed a tendency to have a more favourable outcome in sites with PPD ≥ 7 mm.
Zanatta 2006	Pocket closure was not a planned outcome.
Zijnge 2010	Control, FMS	Percentage of pockets initially measuring ≥ 5 mm and which were reduced to ≤ 3 mm and considered healthy or remained ≥ 5 mm after 3 months	No differences between both groups, significant reductions in both groups.

FMS: full‐mouth scaling: FMD: full‐mouth scaling and disinfection; PD: pocket depth; PPD: probing pocket depth; QRP: quadrant‐wise subgingival scaling and root planing.