| Study | Reason for exclusion |
|---|---|
| Bollen 1998 | 6/16 participants with aggressive periodontitis. Data not shown separately for aggressive and chronic periodontitis. |
| Cortelli 2015 | Same 6 groups of participants as presented in Fonseca 2015; no results of subgroups provided. Results of 3 various FMD or QRP treatment‐modalities presented as 1. |
| Devji 2017 | Commentary of Preus 2013; Preus 2015a; Preus 2017a; Preus 2017b. |
| Eren 2002 | Participants in the intervention arm received FMS for 4 consecutive days (over 24 hours). |
| Jothi 2009 | No QRP control group. |
| Knöfler 2007 | Participants in both arms received a chlorhexidine rinse. |
| Lee 2009 | No randomisation. Quote: "The treatment group was determined according to the patients' preferences". |
| Loggner Graff 2009 | Retreatment of participants after 3 months in study prior to outcome assessment at 6 months. |
| Meulman 2013 | Data only available as figures. No reply from authors to request for supplemental data. |
| Oliveira 2019 | Participants in both arms received azithromycin. |
| Preus 2013 | Participants in all arms received a chlorhexidine rinse. |
| Preus 2015a | Participants in all arms received a chlorhexidine rinse. |
| Preus 2015b | All participants also in placebo arms received a chlorhexidine rinse. |
| Preus 2017a | Participants in all arms received a chlorhexidine rinse. |
| Preus 2017b | Participants in all arms received a chlorhexidine rinse. |
| Quirynen 1995 | 2‐month data only, data for 4 and 8 months later presented in Vandekerckhove 1996 (4‐month data used). |
| Santuchi 2016 | Same group as presented in Santuchi 2015, but outcomes presented insufficiently. |
| Serrano 2011 | 4‐ to 6‐week data only. |
| Silveira 2017 | Participants in both arms received a chlorhexidine rinse and a gel. |
| Tomasi 2006 | 18‐month evaluation after baseline but all participants had several retreatment sessions. These were the same participants as Wennström 2005, but it was an observational follow‐up of the trial. |
| Ushida 2008 | Immunology study with no clinical data. |
| Zhao 2005 | Only preliminary results. In 2020, still no publication on final results. |
FMS: full‐mouth scaling; QRP: quadrant‐wise scaling.