Table 3.

Association of lipoprotein(a) with recurrent cardiovascular events and components of recurrent cardiovascular events by using model 3

End point	Univariate analysis			Multivariate analysisc
	HR	95% CI	P value	HR	95% CI	P value
Lp(a) as a nominal variablea
Primary endpoint	1.819	1.241–2.666	0.002	2.068	1.366–3.132	<0.001
All-cause death	1.230	0.697–2.170	0.475	1.370	0.737–2.550	0.320
Nonfatal stroke	0.866	.0319–2.349	0.778	0.770	0.253–2.346	0.646
Nonfatal MI	1.901	0.621–5.813	0.260	2.239	0.699–7.172	0.175
Unplanned revascularization	3.765	1.896–7.476	<0.001	4.387	2.052–9.382	<0.001
Lp(a) as a continuous variableb
Primary endpoint	1.255	1.094–1.439	0.001	1.285	1.112–1.484	<0.001
All-cause death	1.082	0.855–1.369	0.513	1.104	0.852–1.431	0.453
Nonfatal stroke	0.976	0.631–1.510	0.912	0.897	0.526–1.527	0.688
Nonfatal MI	1.034	0.625–1.711	0.897	1.091	0.662–1.799	0.733
Unplanned revascularization	1.539	1.279–1.851	<0.001	1.588	1.305–1.932	<0.001

CI, confidence interval; HR, hazard ratio; Lp(a), lipoprotein(a); MI, myocardial infarction.

^aThe HR was examined regarding low-Lp(a) group as reference.

^bThe HR was examined by per 1-SD increase of Lp(a).

^cThe multivariate analysis was performed by using model 3.