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Total and broad-spectrum antibiotic days of therapy within 1 week of new abnormal temperature or white blood cell count. Antibiotic days of therapy was defined as the aggregate sum of days for which any amount of a specific antimicrobial agent was received by a patient. For example, if a patient obtained 2 days of vancomycin and 2 days of piperacillin-tazobactam within the 1-week time frame, this would equate to 4 antibiotic days of therapy. Abbreviation: DOT, days of therapy.
