Table 2.
Results of univariate Cox analysis.
| Variables | Number of patients, n (%) | HR | 95% CI for HR | P value |
|---|---|---|---|---|
| Race | ||||
| White | 500 (71.9%) | Reference | .349 | |
| Black | 129 (18.6%) | 1.883 | 1.364–2.599 | <.001*** |
| Other | 66 (9.5%) | 0.667 | 0.360–1.235 | .197 |
| Gender | ||||
| Male | 343 (49.4%) | Reference | ||
| Female | 352 (50.6%) | 0.890 | 0.670–1.200 | .450 |
| Year of diagnosis | ||||
| ≥2014 | 162 (23.3%) | Reference | ||
| <2014 | 533 (76.7%) | 1.014 | 0.611–1.684 | .956 |
| Histology | ||||
| Papillary | 84 (12.1%) | reference | .060 | |
| Adamantinomatous | 236 (34.0%) | 1.460 | 0.830–2.569 | .189 |
| Craniopharyngioma, NOS | 375 (54.0%) | 1.671 | 0.975–2.864 | .062 |
| Surgery types | ||||
| No surgery | 116 (16.7%) | Reference | .014 * | |
| Biopsy/STR | 289 (41.6%) | 0.694 | 0.474–1.016 | .061 |
| GTR | 290 (41.7%) | 0.674 | 0.454–1.000 | .050 * |
| Radiotherapy | ||||
| No | 526 (75.7%) | Reference | ||
| Yes | 169 (24.3%) | 0.670 | 0.460–0.970 | .033 * |
| Tumor size, mm | ||||
| <25 | 207 (29.8%) | Reference | .003 ** | |
| ≥25 | 285 (41.0%) | 1.890 | 1.300–2.747 | <.001*** |
| Unknown | 203 (29.2%) | 1.834 | 1.231–2.732 | .003 ** |
| Age at diagnosis, yr | ||||
| <52 | 358 (51.5%) | Reference | ||
| ≥52 | 337 (48.5%) | 3.500 | 2.600–4.900 | <.001*** |
| Marital status | ||||
| Single | 283 (40.7%) | Reference | .224 | |
| Married | 359 (51.7%) | 0.733 | 0.544–0.987 | .041 * |
| Unknown | 53 (7.6%) | 0.999 | 0.586–1.705 | .998 |
The bold P values indicate significant (P < .05) or marginally significant (P <.15) differences, and the corresponding variables were further analyzed using multivariate Cox model.
CI = confidence interval, GTR = gross total resection, HR= hazard ratio, NOS = not other specific, STR = subtotal resection.
P < .05
P < .01
P < .001.