Table 1.
Demographics and clinical characteristics.
| Variable | Control (n = 60) | IS (n = 60) | P |
|---|---|---|---|
| Age, mean (SD), y | 67.26 (11.2) | 68.17 (9.12) | .246 |
| Female (%) | 24 (40) | 19 (31.6) | .468 |
| Hyperlipidemia (%) | 3 (5) | 18 (30) | .0001 |
| Diabetes (%) | 3 (5) | 22(36.7) | .011 |
| Hypertension history (%) | 6 (10) | 40 (66.7) | .0001 |
| Hcy, mean (SD) | 10.25 (7.79) | 18.32 (5.68) | .001 |
| Cys, mean (SD) | 3.87 (15.64) | 4.88 (6.65) | .872 |
| pNfL, mean (SD) | 105.80 (45.68) | 225.86 (194.71) | .001 |
| NIHSS, mean (SD) | 1 (2.67) | 4.21 (3.47) | .001 |
| mRS, mean (SD) | 0 | 2.38 (1.35) | .0001 |
| BI, mean (SD) | 100 | 70.51(27.89) | .0001 |
pNfL for baseline at day 2, P ≤ .05; P ≤ .0001.
BI = Barthel Index; Cys = cystatin; Hcy = homocysteine; mRS = Modified Rankin scale; NIHSS = National Institutes of Health Stroke Scale; pNfL = plasma neurofilament light chain at day 2.