Figure 4.

Immunostaining of LTV1 in control and patient skin. (A) In control skin there is diffuse cytoplasmic staining within the basal keratinocytes, with additional granular perinuclear labelling seen at higher magnification. The intensity of the staining is evenly distributed along the basal keratinocyte layer within the skin section. (B) In patient skin, the immunoreactivity for LTV1 is slightly reduced. Of note, staining along the basal layer is uneven with some basal keratinocytes showing barely any immunostaining.