Table 2.
List of genes specifically regulated in the biliary atresia samples over both diseased control (non-BA) and normal control (NC).
| Gene symbol | Adjusted P value | Fold change | Description | ||
|---|---|---|---|---|---|
| BA-NC | BA-non-BA | BA-NC | BA-non-BA | ||
| Upregulated genes | |||||
| EPCAM | 4.73E-25 | 4.56E-05 | 4.37 | 1.29 | Epithelial cell adhesion molecule |
| SPP1 | 8.86E-17 | 4.56E-05 | 3.26 | 1.37 | Secreted phosphoprotein 1 |
| ANKRD1 | 4.14E-10 | 1.73E-06 | 3.11 | 2.05 | Ankyrin repeat domain 1 |
| MMP7 | 3.76E-08 | 8.21E-05 | 2.94 | 1.85 | Matrix metallopeptidase 7 |
| LUM | 3.21E-12 | 6.17E-05 | 2.70 | 1.26 | Lumican |
| RGS4 | 7.25E-12 | 5.86E-04 | 2.54 | 1.03 | Regulator of G-protein signaling 4 |
| EMP1 | 1.16E-05 | 1.96E-03 | 2.40 | 1.41 | Epithelial membrane protein 1 |
| CFTR | 1.41E-08 | 2.82E-03 | 2.33 | 1.05 | Cystic fibrosis transmembrane conductance regulator |
| HAS2 | 3.69E-06 | 1.62E-04 | 2.28 | 1.56 | Hyaluronan synthase 2 |
| KRT23 | 1.34E-08 | 5.29E-04 | 2.19 | 1.14 | Keratin 23 |
| VCAN | 6.40E-10 | 1.52E-05 | 2.12 | 1.32 | Versican |
| CXCL8 | 3.55E-09 | 4.56E-05 | 1.93 | 1.20 | C-X-C motif chemokine ligand 8 |
| CCL20 | 1.75E-03 | 1.14E-02 | 1.87 | 1.24 | C-C motif chemokine ligand 20 |
| VTCN1 | 4.14E-08 | 1.11E-04 | 1.81 | 1.09 | V-set domain containing T cell activation inhibitor 1 |
| ITGA2 | 6.29E-07 | 1.50E-04 | 1.68 | 1.10 | Integrin subunit alpha 2 |
| SERPINE1 | 1.28E-02 | 9.47E-03 | 1.53 | 1.36 | Serpin family E member 1 |
| THBS1 | 5.61E-06 | 3.54E-04 | 1.52 | 1.00 | Thrombospondin 1 |
| CCL2 | 2.51E-04 | 4.05E-05 | 1.38 | 1.37 | C-C motif chemokine ligand 2 |
| TM4SF1 | 1.14E-03 | 1.52E-05 | 1.38 | 1.71 | Transmembrane 4 L six family member 1 |
| LAMC2 | 1.99E-06 | 4.56E-05 | 1.35 | 1.02 | Laminin subunit gamma 2 |
| AREG | 6.89E-03 | 2.44E-03 | 1.34 | 1.28 | Amphiregulin |
| SLC2A3 | 1.05E-02 | 2.66E-03 | 1.15 | 1.16 | Solute carrier family 2 member 3 |