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. 2022 Jul;28(7):1375–1383. doi: 10.3201/eid2807.212330

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Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.

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Self-reported and objective reactions following the third vaccine dose, stratified by age, sex, and underlying medical condition for self-reported and physiologic reactions to third BNT162b2 (Pfizer, https://www.pfizer.com) mRNA coronavirus disease vaccine doses. Reactions reported by participants through the mobile application (A, C, E) and objective heart rate and heart rate variability measured through a smartwatch (B, D, F) are shown, stratified by age (A, B), sex (C, D), and underlying medical condition (E, F). Bars indicate percentage of participants with a reported or recorded reaction; error bars indicate 90% CIs.