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. 2022 Jun 28;12:263. doi: 10.1038/s41398-022-02026-5

Table 4.

Safety outcomes: N-acetylcysteine versus placebo.

N n RR (95% CI) P value I2
Insomnia 2 73 1.35 (0.32, 5.82) 0.68 7%
Somnolence 3 120 1.42 (0.72, 2.79) 0.31 0%
Fatigue 3 113 1.22 (0.43, 3.48) 0.70 35%
Dizziness 4 186 1.38 (0.70, 2.74) 0.35 0%
Headache 3 120 0.92 (0.44, 1.91) 0.81 0%
Dry mouth 3 146 0.95 (0.39, 2.34) 0.91 0%
Nausea/vomiting 7 323 1.15 (0.53, 2.50) 0.72 46%
Diarrhea 6 228 1.96 (0.78, 4.92) 0.15 0%
Constipation 4 186 0.88 (0.42, 1.84) 0.74 0%
Rash 3 84 2.90 (0.49, 17.29) 0.24 0%

95% CI 95% confidence interval, N number of studies, n number of patients, RR risk ratio.