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. 2022 Jun 28;12:10891. doi: 10.1038/s41598-022-15023-x

Table 3.

Results of multiple regression analyses to estimate the association between myopia and corneal higher order aberrations (evaluated with natural pupillary diameters, average value φ = 6.1 mm).

Axial length, mm (N = 59) Cycloplegic objective refraction, D (N = 25)
β 95% CI P β 95% CI P
Overall
Age (years) 0.176 0.073 to 0.279 0.001 0.142 − 0.323 to 0.606 0.56
Gender 0.258 − 0.320 to 0.836 0.39 − 0.795 − 2.69 to 1.10 0.42
SA (μm) − 0.633 − 3.26 to 1.99 0.64 10.2 − 27.3 to 47.8 0.60
S3 (μm) − 11.2 − 32.8 to 10.4 0.32 11.3 − 71.3 to 93.9 0.79
S4 (μm) − 3.63 − 29.9 to 22.7 0.79 − 36.9 − 202 to 128 0.67
THOA (μm) 9.75 − 19.0 to 38.5 0.51 5.98 − 109 to 121 0.92
R2 0.294 0.421

D diopters, SA spherical aberration, S3 3rd-order aberrations, S4 4th-order aberrations, THOA sum of the 3rd- to 6th-order aberrations, 95% CI 95% confidence interval, β coefficient.

Two multiple regression models were used. Axial length or cycloplegic objective refraction was used as the outcome variable. P < 0.05 are highlighted. For gender, boys were numbered 1 and girls were numbered 0.